Bioinformatics : Methods And Applications Genomics, Proteomics And Drug Discovery

Designed as a text for students and professionals pursuing careers in the fields of molecular biology, pharmacy and bioinformatics, this third edition continues to offer a fascinating and authoritative treatment of the entire spectrum of bioinformatics, covering a wide range of high-throughput technologies. In this edition, three new chapters are included along with the coverage of recent advances in microarray technologies and their applications.

As a student-friendly text, it embodies several pedagogic features such as detailed examples, chapter-end problems, numerous tables, a large number of diagrams, flow charts, a comprehensive glossary and an up-to-date bibliography. This book should prove an invaluable asset to students and researchers in the fields of bioinformatics, biotechnology, computer-aided drug design, information technology, medical diagnostics, molecular biology and pharmaceutical industry.

NEW TO THE THIRD EDITION

 A separate chapter on Structural Biology and Virtual Screening focuses on computational methods for predicting functional regions of target proteins for drug development to boost success rate.

 A new chapter on Biomarkers introduces the students to various biomarker strategies and practices for the development of new drugs.

 The chapter on Ion Channels and Aquaporins discusses their fundamental roles in drug development.

KEY FEATURES

 State-of-the-art technologies for gene identification, molecular modeling and monitoring of cellular processes

 Data mining, analysis, classification, interpretation and efficient structure determination of genomes and proteomes

 Importance of cell cycle for discovering new drug targets and their ligands

 Computer-aided drug design and ADME-Tox property prediction