From Genes To Genomes: Concepts And Applications Of Dna Technology

From Genes to Genomes: Concepts and Applications of DNA Technology, Second Edition
Jeremy W. Dale and Malcolm von Schantz, "University of Surrey," "UK,"

Rapid advances in a collection of techniques referred to as gene technology, genetic engineering, recombinant DNA technology and gene cloning have pushed molecular biology to the forefront of the biological sciences. "From Genes to Genomes: Concepts and Applications of DNA Technology, Second Edition" explains key ideas underlying the most central techniques in the context of the ways in which they are used. As well as an overall update of the material, this new edition includes the strengthening of the gene to genome theme, additional emphasis on proteomics, gene therapy and stem cells, and more eukaryotic/mammalian examples.

Opening with a brief review of the basic concepts of molecular biology, followed by a description of the key molecular methods and how they fit together, the book progresses from the cloning, characterisation and manipulation of individual genes through to genome sequence and analysis, and the genome-wide study of transcription and translation. Finally, the book introduces the use of these techniques for genetic modification of organisms, ranging from live vaccines to transgenic plants and animals, including the prospects for gene therapy.

An accessible introduction to the key concepts and techniques in an exciting and rapidly developing field. Includes basic concepts as well as the latest developments. Introduces selected aspects of bioinformatics. Clear presentation with two-colour design throughout.

The new edition of this concise, clearly written textbook will prove invaluable to thosestudying intermediate molecular genetics within the biological and biomedical sciences as well as established researchers needing to update their knowledge of this fast moving field.

Rapid advances in a collection of techniques referred to as gene technology, genetic engineering, recombinant DNA technology and gene cloning have pushed molecular biology to the forefront of the biological sciences. This new edition of a concise, well-written textbook introduces key techniques and concepts involved in cloning genes and in studying their expression and variation.

The book opens with a brief review of the basic concepts of molecular biology, before moving on to describe the key molecular methods and how they fit together. This ranges from the cloning and study of individual genes to the sequencing of whole genomes, and the analysis of genome-wide information. Finally, the book moves on to consider some of the applications of these techniques, in biotechnology, medicine and agriculture, as well as in research that is causing the current explosion of knowledge across the biological sciences.

"From Genes to Genomes: Concepts and Applications of DNA Technology, Second Edition" includes full two-colour design throughout and an accompanying website. Specific changes for the new edition include: Strengthening of gene to genome theme Updating and reinforcing of material on proteomics, gene therapy and stem cells More eukaryotic/mammalian examples and less focus on bacteria

This textbook is must-have for all undergraduates studying intermediate molecular genetics within the biological and biomedical sciences. It is also of interest for researchers and all those needing to update their knowledge of this rapidly moving field.

From the reviews of the first edition:

"This monograph is excellently organized.... an outstanding addition to the library of anundergraduate or graduate student and a useful aid for the libraries of mentors of undergraduate studies."
--"BIOCHEMISTRY AND MOLECULAR EDUCATION"

.,."this lucid book provides very nice descriptions of many of the modern methods in molecular biology.."
--"ASM NEWS"