“stephen t holgate”

This timely volume brings together the latest basic and clinical insights on the cellular and mediator mechanisms involved in the induction and persistence of airway dysfunction of asthma by over 90 experts in the field-paving the way for developing novel and more effective antiinflammatory therapeu... More

Immunopharmacology represents the boundary between the immune system and chemical mediators of the inflammatory and neuroendocrine responses. The subject as applied to the respiratory system embraces most of the common non-malignant lung diseases of which asthma and allied disorders are the most pre... More

This unique and innovative book explains how to improve maintenance and reliability performance at the plant level by changing the organization's culture. It is specifically intended for middle managers in the manufacturing and process industries. Includes a PowerPoint presentation on audio on the e... More

As both an immunological disease and a condition of tissue remodeling, asthma involves a number of inflammatory as well as structural cells that interact in response to stimuli present in the environment. Through numerous well-designed schematics, macro- and microscopic pictures, tables, and researc... More

This book is a comprehensive introduction to the study of politics, political concepts and ideas, the varieties of political systems, the main political movements and the core issues which will dominate politics in the twenty-first century. The third edition has been fully updated to include the mos... More

This book brings a new approach to the subject of asthma, highlighting the current areas of controversy and debate. A wide spectrum, ranging from clinical investigation into the scientific basis of the disease through to its management and prognosis is covered. In each section, a selection of contro... More

Little new has been introduced into the armamentarium for asthma therapy in the last thirty years apart from improvements in b2-adrenoceptor agonists, corticosteroids and cysteinyl leukotriene antagonists. However, the introduction of a fully humanised monoclonal antibody to immunoglobulin E (IgE) (... More

Allergic diseases are complex and involve a range of environmental factors interacting with a susceptible genotype. The familial clustering of diseases, such as asthma and hay fever, has been recognised for over two centuries, but identification of the genetic basis to this had to await the molecula... More