Williams Textbook of Endocrinology 12 Edition

The latest edition of Williams Textbook of Endocrinology edited by Drs. Shlomo Melmed, Kenneth S. Polonsky, P. Reed Larsen, and Henry M. Kronenberg, helps you diagnose and treat your patients effectively with up-to-the minute, practical know-how on all endocrine system disorders. Comprehensive yet accessible, this extensively revised 12th Edition updates you on diabetes, metabolic syndrome, obesity, thyroid disease, testicular disorders, and much more so you can provide your patients with the most successful treatments. Find scientific insight and clinical data interwoven in every chapter, reflecting advances in both areas of this constantly changing discipline, and presented in a truly accessible format. You'll also access valuable contributions from a dynamic list of expert authors and nearly 2.000 full-color images to help you with every diagnosis.

Key Features

• Chapters bridge the gap between basic science and clinical applications, providing the right context for optimal diagnosis and treatment.
• Chapters by the leading authorities in endocrinology equip you with authoritative opinions on any challenge you face.

New to This Edition

• New chapters on hormones and athletic performance neuro endocrine control of appetite and body weight and HIV/AIDS keep you up to date on these timely topics.
• New evidence-based screening algorithms and treatment boxes deliver reliable clinical guidance at a glance.
• New full-color illustrations throughout help you grasp essential concepts easily.
• Full-text on-line access lets you search the book instantly on your computer and download images for your next presentation.

About the Author
Henry M. Kronenberg MD, Professor of Medicine, Harvard Medical School; Chief, Endocrine Unit, Massachusetts General Hospital, Boston, MA. Shlomo Melmed, MD, Professor of Medicine and Associate Dean, UCLA School of Medicine; Senior Vice President for Academic Affairs, Cedars Sinai Medical Center, Los Angeles, CA. Kenneth S. Polonsky, MD, Adolphus Busch Professor and Chair, Department of Medicine, Professor of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO.

P. Reed Larsen, MD, FACP, FRCP, Professor of Medicine, Harvard Medical School; Chief, Division of Endocrinology, Diabetes and Hypertension, Brigham and Women???s Hospital, Boston, MA.

Table of Contents
Section I: Hormones and Hormone Action

Chapter 1: Principles of Endocrinology: H. Kronenberg/S. Melmed/K. Polonsky/P. Larsen
Chapter 2: The Endocrine Patient: D. Federman
Chapter 3: Genetic Control of Peptide Hormone Formation: J. Habener
Chapter 4: Mechanism of Action of Hormones that Act on Nuclear Receptors: M. Lazar
Chapter 5: Mechanism of Action of Hormones that Act at the Cell Surface: A. Spiegel/C. Su/S. Taylor
Chapter 6: Laboratory Techniques for Recognition of Endocrine Disorders: G. Klee

Section II: Hypothalamus and Pituitary

Chapter 7: (Classic) Neuroendocrinology: M. Low
Chapter 8: Anterior Pituitary: S. Melmed/D. Kleinberg
Chapter 9: Posterior Pituitary: A. Robinson

Section III: Thyroid

Chapter 10: Thyroid Physiology and Diagnostic Evaluation of Patients with Thyroid Disorders: P. Larsen/T. Davies/M. Schlumberger/I. Hay
Chapter 11: Thyrotoxicosis: T. Davies/P. Larsen
Chapter 12: Hypothyroidism and Thyroiditis: G. Brent/T. Davies/P. Larsen
Chapter 13: Nontoxic Goiter and Thyroid Neoplasia: M. Schlumberger/I. Hay/S. Filetti

Section IV: Adrenal Cortex and Endocrine Hypertension

Chapter 14: The Adrenal Cortex: P. Stewart
Chapter 15: Endocrine Hypertension: W. Young

Section V: Reproduction

Chapter 16: The Physiology and Pathology of the Female Reproductive Axis: S. Bulun/Y. Adashi
Chapter 17: Fertility Control: Current Approaches and Global Aspects: M. Kafrissen/E. Adashi/P. Darney
Chapter 18: Disorders of the Testes and the Male Reproductive Tract: S. Bhasin
Chapter 19: Sexual Dysfunction in Men and Women: S. Bhasin/W. Hellstrom/R. Rosen

Section VI: Endocrinology and the Life Span

Chapter 20: Endocrine Changes in Pregnancy: G. Braunstein
Chapter 21: Endocrinology of Fetal Development: D. Fisher
Chapter 22: Disorders of Sex Differentiation: I. Hughes
Chapter 23: Normal and Aberrant Growth: E. Reiter/R. Rosenfeld
Chapter 24: Puberty: Ontogeny, Neuroendocrinology, Physiology, and Disorders: D. Styne/M. Grumbach
Chapter 25: Hormones and Athletic Performance: C. Strasburger/E. Ghigo/F. Lanfranco
Chapter 26: Endocrinology of Aging: S. Lamberts

Section VII: Mineral Metabolism

Chapter 27: Hormones and Disorders of Mineral Metabolism: F. Bringhurst/M. Demay/H. Kronenberg
Chapter 28: Metabolic Bone Disease: L. Raisz/B. Kream/J. Lorenzo
Chapter 29: Kidney Stones: R. Monk/D. Bushinsky

Section VIII: Disorders of Carbohydrates and Metabolism

Chapter 30: Type 2 Diabetes Mellitus: J. Buse/K. Polonsky/C. Burant
Chapter 31: Type 1 Diabetes: G. Eisenbarth/K. Polonsky/J. Buse
Chapter 32: Complications of Diabetes Mellitus: M. Brownlee
Chapter 33: Glucose Homeostasis and Hypoglycemia: P. Cryer

Section IX: Body Fat and Lipid Metabolism

Chapter 34: Neuroendocrine Control of Appetite and Body Weight: J. Elmquist/R. Cone
Chapter 35: Obesity: S. Klein
Chapter 36: Disorders of Lipid Metabolism: R. Mahley
Chapter 37: Endocrinology of HIV/AIDS: Grinspoon
Chapter 38: Gastrointestinal Hormonal Disorders: D. Drucker

Section X: Polyendocrine Disorders

Chapter 39: Pathogenesis of Endocrine Tumors: A. Arnold
Chapter 40: Multiple Endocrine Neoplasia: R. Gagel/S. Marx
Chapter 41: Immunoendocrinopathy Syndromes: G. Eisenbarth/P. Gottlieb/Barker

Section XI: Paraendocrine and Neoplastic Syndromes Chapter 42: Endocrine-Responsive Cancer: R. Santen
Chapter 43: Hormonal Manifestations of Malignancy: G. Strewler
Chapter 44: Carcinoid Tumors, Carcinoid Syndrome and Related Disorders: K. Qberg