This book presents the Introduction, Data Structures, Control Statements, Functions, Classes & Objects, Inheritance, Operator Overloading, Errors & Exceptions, File Handling, Databases, Pandas and NumPy. It is meant to be utilized as a reading material for one semester course in Python Programming at the Graduate or Post Graduate level, and as a kind of perspective book. We will probably give an in-depth and out-to-date and significant aspects of Python Programming, and related innovations.