Infections in children often lead to dilemmas in diagnosis and needs rational anti-microbial prescribing. In continuation with the first part of Infection in Children book series, this book again deals with various infections in clinical practice and an approach to them. The cases are represented in a system wise manner. Latest guidelines with evidence based practice are discussed here. This novel case based approach deals with likely dilemmas that one may face when dealing with these infections. In addition to CNS, respiratory, liver infections, TB and HIV, this book also discusses an approach to pyrexia of unknown origin (PUO), rational antibiotic prescribing in various infections, a clinical approach to URTI, LRTI, various cough syrups and role of nebulization in LRTI. Various hot topics like recurrent malaria, recurrent typhoid are discussed in detail.