Neem oil should only be used externally on the skin and has been therapeutically used as folk medicine to control respiratory disorders, constipation, leprosy, as well as a general tonic. It has been used for the topical treatment of rheumatism, eczema, ringworm, athlete's foot, cold sores, psoriasis, warts, chronic syphilitic sores, infected burn wounds and slow-healing skin ulcers as well as controlling various skin infections