Optimized Response-Adaptive Clinical Trials

Optimized Response-Adaptive Clinical Trials (English, Paperback, Ondra Thomas)

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Author
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Highlights
  • Language: English
  • Binding: Paperback
  • Publisher: Springer Fachmedien Wiesbaden
  • Genre: Mathematics
  • ISBN: 9783658083434, 9783658083434
  • Pages: 102
Description
Two-armed response-adaptive clinical trials are modelled as Markov decision problems to pursue two overriding objectives: Firstly, to identify the superior treatment at the end of the trial and, secondly, to keep the number of patients receiving the inferior treatment small. Such clinical trial designs are very important, especially for rare diseases. Thomas Ondra presents the main solution techniques for Markov decision problems and provides a detailed description how to obtain optimal allocation sequences.
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Specifications
Book Details
Imprint
  • Springer Spektrum
Dimensions
Height
  • 210 mm
Length
  • 148 mm
Weight
  • 1657 gr
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