This two volume set presents clinicians with the scientific proceedings from the 2025 APICON (Annual Conference of the Association of Physicians of India). Each section is dedicated to diseases and disorders encountered in a different system of the body, helping both with postgraduate exam preparation and daily clinical decision making. The extensive content, comprising nearly 2700 pages, provides the most recent advances and evidence-based guidelines for medical management. Expert insights on molecular biology, genetics, and the role of artificial intelligence in diagnosis and treatment, are also included. Accompanying this invaluable manual, are two complimentary books - Progress in Medicine 2025 and API Medicine: A Clinical Companion.