Whole-Body Systemic Enzyme for Healthy Circulation Dietary Supplement Nattokinase is a systemic enzyme isolated from the traditional Japanese soy food natto. It has been shown to support healthy blood flow by assisting the circulatory clearing system of the body. Suggested Use 1 capsule three times daily on an empty stomach with 8 ounces of water. Other Ingredients Microcrystalline cellulose, gelatin (capsule), colloidal silicon dioxide, and magnesium stearate. Contains soy. Warnings Store in a cool, dry place. Do not use if you have blood coagulation or blood pressure disorder. Consult your healthcare professional before taking this product if you are taking any drug that effects blood coagulation or blood pressure such as prescription vitamin K, heparin, warfarin (Coumadin), diuretics, ACE inhibitors, or beta blockers, or if you are pregnant, may become pregnant, or breastfeeding. Do not use if either tamper-evident seal is broken or missing. Keep out of the reach of children.